Ontology highlight
ABSTRACT:
SUBMITTER: Price AL
PROVIDER: S-EPMC2211542 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Price Alkes L AL Butler Johannah J Patterson Nick N Capelli Cristian C Pascali Vincenzo L VL Scarnicci Francesca F Ruiz-Linares Andres A Groop Leif L Saetta Angelica A AA Korkolopoulou Penelope P Seligsohn Uri U Waliszewska Alicja A Schirmer Christine C Ardlie Kristin K Ramos Alexis A Nemesh James J Arbeitman Lori L Goldstein David B DB Reich David D Hirschhorn Joel N JN
PLoS genetics 20071119 1
European Americans are often treated as a homogeneous group, but in fact form a structured population due to historical immigration of diverse source populations. Discerning the ancestry of European Americans genotyped in association studies is important in order to prevent false-positive or false-negative associations due to population stratification and to identify genetic variants whose contribution to disease risk differs across European ancestries. Here, we investigate empirical patterns of ...[more]