Ontology highlight
ABSTRACT:
SUBMITTER: Koo SH
PROVIDER: S-EPMC2211573 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
Koo Seok Hwee SH Ong Tan Ching TC Chong Kok Ting KT Lee Caroline Guat Lay CG Chew Fook Tim FT Lee Edmund Jon Deoon EJ
Biological procedures online 20071101
We have developed and validated a consolidated bead-based genotyping platform, the Bioplex suspension array for simultaneous detection of multiple single nucleotide polymorphisms (SNPs) of the ATP-binding cassette transporters. Genetic polymorphisms have been known to influence therapeutic response and risk of disease pathologies. Genetic screening for therapeutic and diagnostic applications thus holds great promise in clinical management. The allele-specific primer extension (ASPE) reaction was ...[more]