Ontology highlight
ABSTRACT:
SUBMITTER: Shichijo S
PROVIDER: S-EPMC2212124 | biostudies-literature | 1998 Feb
REPOSITORIES: biostudies-literature
Shichijo S S Nakao M M Imai Y Y Takasu H H Kawamoto M M Niiya F F Yang D D Toh Y Y Yamana H H Itoh K K
The Journal of experimental medicine 19980201 3
Except for melanomas, tumor antigens recognized by cytotoxic T lymphocytes (CTLs) are yet unidentified. We have identified a gene encoding antigenic peptides of human squamous cell carcinomas (SCCs) recognized by human histocompatibility leukocyte antigens (HLA)- A2601-restricted CTLs. This gene showed no similarity to known sequences, and encoded two (125- and 43-kilodalton [kD]) proteins. The 125-kD protein with the leucine zipper motif was expressed in the nucleus of the majority of prolifera ...[more]