In silico and in vitro comparative analysis to select, validate and test SNPs for human identification.
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ABSTRACT:
SUBMITTER: Giardina E
PROVIDER: S-EPMC2222643 | biostudies-literature | 2007 Dec
REPOSITORIES: biostudies-literature
Publications
In silico and in vitro comparative analysis to select, validate and test SNPs for human identification.
Giardina Emiliano E Pietrangeli Ilenia I Martone Claudia C Asili Paola P Predazzi Irene I Marsala Patrizio P Gabriele Luciano L Pipolo Claudio C Ricci Omero O Solla Gianluca G Sineo Luca L Spinella Aldo A Novelli Giuseppe G
BMC genomics 20071212
<h4>Background</h4>The recent advances in human genetics have recently provided new insights into phenotypic variation and genome variability. Current forensic DNA techniques involve the search for genetic similarities and differences between biological samples. Consequently the selection of ideal genomic biomarkers for human identification is crucial in order to ensure the highest stability and reproducibility of results.<h4>Results</h4>In the present study, we selected and validated 24 SNPs wh ...[more]
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