The BaeSR two-component regulatory system mediates resistance to condensed tannins in Escherichia coli.
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ABSTRACT:
SUBMITTER: Zoetendal EG
PROVIDER: S-EPMC2223256 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
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The BaeSR two-component regulatory system mediates resistance to condensed tannins in Escherichia coli.
Zoetendal Erwin G EG Smith Alexandra H AH Sundset Monica A MA Mackie Roderick I RI
Applied and environmental microbiology 20071126 2
The gene expression profiles of Escherichia coli strains grown anaerobically with or without Acacia mearnsii (black wattle) extract were compared to identify tannin resistance strategies. The cell envelope stress protein gene spy and the multidrug transporter-encoding operon mdtABCD, both under the control of the BaeSR two-component regulatory system, were significantly up-regulated in the presence of tannins. BaeSR mutants were more tannin sensitive than their wild-type counterparts. ...[more]
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