YadBC of Yersinia pestis, a new virulence determinant for bubonic plague.
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ABSTRACT:
SUBMITTER: Forman S
PROVIDER: S-EPMC2223446 | biostudies-literature | 2008 Feb
REPOSITORIES: biostudies-literature
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yadBC of Yersinia pestis, a new virulence determinant for bubonic plague.
Forman Stanislav S Wulff Christine R CR Myers-Morales Tanya T Cowan Clarissa C Perry Robert D RD Straley Susan C SC
Infection and immunity 20071119 2
In all Yersinia pestis strains examined, the adhesin/invasin yadA gene is a pseudogene, yet Y. pestis is invasive for epithelial cells. To identify potential surface proteins that are structurally and functionally similar to YadA, we searched the Y. pestis genome for open reading frames with homology to yadA and found three: the bicistronic operon yadBC (YPO1387 and YPO1388 of Y. pestis CO92; y2786 and y2785 of Y. pestis KIM5), which encodes two putative surface proteins, and YPO0902, which lack ...[more]
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2010-12-07 | GSE22299 | GEO