Ontology highlight
ABSTRACT:
SUBMITTER: Nordgren J
PROVIDER: S-EPMC2224280 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Nordgren Johan J Bucardo Filemón F Dienus Olaf O Svensson Lennart L Lindgren Per-Eric PE
Journal of clinical microbiology 20071024 1
Norovirus is now recognized as the leading cause of nonbacterial acute gastroenteritis in adults, causing numerous outbreaks worldwide. We have developed two novel light-upon-extension (LUX) real-time PCR assays for detection and quantification of norovirus genogroups I and II. The LUX system uses a fluorophore attached to one primer having a self-quenching hairpin structure, making it cost-effective and specific. The assays were evaluated against clinical stool specimens (n = 103) from Sweden a ...[more]