Ontology highlight
ABSTRACT:
SUBMITTER: Quezada G
PROVIDER: S-EPMC2224773 | biostudies-literature | 2008 Feb
REPOSITORIES: biostudies-literature
Quezada Gerardo G Koshkina Nadezhda V NV Zweidler-McKay Patrick P Zhou Zichao Z Kontoyiannis Dimitrios P DP Kleinerman Eugenie S ES
Antimicrobial agents and chemotherapy 20071105 2
We demonstrated that intranasal granulocyte-macrophage colony-stimulating factor given to immunosuppressed mice infected with pulmonary aspergillosis resulted in a sixfold reduction in the lung fungal burden compared to the result for saline-treated mice (P = 0.045). These data suggest that lung-targeted immunotherapy may be complementary to antifungal agents and may improve patient responses. ...[more]