Ontology highlight
ABSTRACT:
SUBMITTER: Zou J
PROVIDER: S-EPMC2234233 | biostudies-literature | 2008 Feb
REPOSITORIES: biostudies-literature
Zou Jianwei J Hallen Mark A MA Yankel Christine D CD Endow Sharyn A SA
The Journal of cell biology 20080204 3
The kinesin-13 motor, KLP10A, destabilizes microtubules at their minus ends in mitosis and binds to polymerizing plus ends in interphase, regulating spindle and microtubule dynamics. Little is known about kinesin-13 motors in meiosis. In this study, we report that KLP10A localizes to the unusual pole bodies of anastral Drosophila melanogaster oocyte meiosis I spindles as well as spindle fibers, centromeres, and cortical microtubules. We frequently observe the pole bodies attached to cortical mic ...[more]