Ontology highlight
ABSTRACT:
SUBMITTER: Anelli T
PROVIDER: S-EPMC2234347 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Anelli Tiziana T Sitia Roberto R
The EMBO journal 20080101 2
Eukaryotic cells are able to discriminate between native and non-native polypeptides, selectively transporting the former to their final destinations. Secretory proteins are scrutinized at the endoplasmic reticulum (ER)-Golgi interface. Recent findings reveal novel features of the underlying molecular mechanisms, with several chaperone networks cooperating in assisting the maturation of complex proteins and being selectively induced to match changing synthetic demands. 'Public' and 'private' cha ...[more]