Ontology highlight
ABSTRACT:
SUBMITTER: Little RF
PROVIDER: S-EPMC2234790 | biostudies-literature | 2007 Dec
REPOSITORIES: biostudies-literature
Little Richard F RF Aleman Karen K Kumar Pallavi P Wyvill Kathleen M KM Pluda James M JM Read-Connole Elizabeth E Wang Victoria V Pittaluga Stefania S Catanzaro Andrew T AT Steinberg Seth M SM Yarchoan Robert R
Blood 20070910 13
Thirty-six patients with AIDS-associated Kaposi sarcoma (KS) requiring chemotherapy were treated for six 3-week cycles of pegylated liposomal doxorubicin (20 mg/m(2)) plus interleukin-12 (IL-12; 300 ng/kg subcutaneously twice weekly), followed by 500 ng/kg subcutaneous IL-12 twice weekly for up to 3 years. All received highly active antiretroviral therapy (HAART). Twenty-two had poor-prognosis KS (T(1)S(1)). Thirty patients had a major response, including 9 with complete response, yielding an 83 ...[more]