Ontology highlight
ABSTRACT:
SUBMITTER: Mukherjee M
PROVIDER: S-EPMC2242546 | biostudies-literature | 2006 Jun
REPOSITORIES: biostudies-literature
Mukherjee Munia M Dutta Kaushik K White Mark A MA Cowburn David D Fox Robert O RO
Protein science : a publication of the Protein Society 20060601 6
Flaviviruses cause many human diseases, including dengue fever, yellow fever, West Nile viral encephalitis, and hemorrhagic fevers, and are transmitted to their vertebrate hosts by infected mosquitoes and ticks. Domain III of the envelope protein (E-D3) is considered to be the primary viral determinant involved in the virus-host-cell receptor interaction, and thus represents an excellent target for antiviral drug development. Langat (LGT) virus is a naturally attenuated BSL-2 TBE virus and is a ...[more]