Ontology highlight
ABSTRACT:
SUBMITTER: Jagoe WN
PROVIDER: S-EPMC2242937 | biostudies-literature | 2006 Jul
REPOSITORIES: biostudies-literature
Jagoe William N WN Jackson Sarah R SR Lindsay Andrew J AJ McCaffrey Mary W MW Khan Amir R AR
Acta crystallographica. Section F, Structural biology and crystallization communications 20060626 Pt 7
The small GTPase Rab11 regulates the recycling of endosomes back to the plasma membrane. In its active GTP-bound form, Rab11 binds a novel set of effectors termed the Rab11 family of interacting proteins (Rab11-FIPs) which contain a conserved C-terminal Rab-binding domain (RBD) of unknown structure. Here, a complex of Rab11 with the RBD of Rab11-FIP2 has been purified and crystallized in the trigonal space group P3(1)21, with unit-cell parameters a = 64.99, b = 64.99, c = 112.59 angstroms. Stati ...[more]