Ontology highlight
ABSTRACT:
SUBMITTER: Fearnside JF
PROVIDER: S-EPMC2244706 | biostudies-literature | 2008 Feb
REPOSITORIES: biostudies-literature
Fearnside Jane F JF Dumas Marc-Emmanuel ME Rothwell Alice R AR Wilder Steven P SP Cloarec Olivier O Toye Ayo A Blancher Christine C Holmes Elaine E Tatoud Roger R Tatoud Roger R Barton Richard H RH Scott James J Nicholson Jeremy K JK Gauguier Dominique D
PloS one 20080227 2
Insulin resistance plays a central role in type 2 diabetes and obesity, which develop as a consequence of genetic and environmental factors. Dietary changes including high fat diet (HFD) feeding promotes insulin resistance in rodent models which present useful systems for studying interactions between genetic background and environmental influences contributing to disease susceptibility and progression. We applied a combination of classical physiological, biochemical and hormonal studies and pla ...[more]