Genetic variability of immunomodulatory genes in ectromelia virus isolates detected by denaturing high-performance liquid chromatography.
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ABSTRACT:
SUBMITTER: Ribas G
PROVIDER: S-EPMC224613 | biostudies-literature | 2003 Sep
REPOSITORIES: biostudies-literature
Publications
Genetic variability of immunomodulatory genes in ectromelia virus isolates detected by denaturing high-performance liquid chromatography.
Ribas Gloria G Rivera Jose J Saraiva Margarida M Campbell R Duncan RD Alcami Antonio A
Journal of virology 20030901 18
The genetic variability of nine genes in 12 isolates and strains of ectromelia virus, which causes a smallpox-like disease (mousepox) in mice, was determined and allows for classification of ectromelia viruses. The low genetic variability suggests that evolutionary pressure maintains the activity of immunomodulatory genes in natural poxvirus infections. ...[more]
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