Role of PACS-1 in trafficking of human cytomegalovirus glycoprotein B and virus production.
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ABSTRACT:
SUBMITTER: Crump CM
PROVIDER: S-EPMC224974 | biostudies-literature | 2003 Oct
REPOSITORIES: biostudies-literature
Publications
Role of PACS-1 in trafficking of human cytomegalovirus glycoprotein B and virus production.
Crump Colin M CM Hung Chien-Hui CH Thomas Laurel L Wan Lei L Thomas Gary G
Journal of virology 20031001 20
The final envelopment of herpesviruses during assembly of new virions is thought to occur by the budding of core viral particles into a late secretory pathway organelle, the trans-Golgi network (TGN), or an associated endosomal compartment. Several herpesvirus envelope glycoproteins have been previously shown to localize to the TGN when expressed independently from other viral proteins. In at least some cases this TGN localization has been shown to be dependent on clusters of acidic residues wit ...[more]
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