Ontology highlight
ABSTRACT:
SUBMITTER: Venkitaramani DV
PROVIDER: S-EPMC2253341 | biostudies-literature | 2005 Jul
REPOSITORIES: biostudies-literature
Venkitaramani Deepa V DV Fulton D Bruce DB Andreotti Amy H AH Johansen Kristen M KM Johansen Jørgen J
Protein science : a publication of the Protein Society 20050603 7
Calsensin is an EF-hand calcium-binding protein expressed by a subset of peripheral sensory neurons that fasciculate into a single tract in the leech central nervous system. Calsensin is a 9-kD protein with two EF-hand calcium-binding motifs. Using multidimensional NMR spectroscopy we have determined the solution structure and backbone dynamics of calcium-bound Calsensin. Calsensin consists of four helices forming a unicornate-type four-helix bundle. The residues in the third helix undergo slow ...[more]