Ontology highlight
ABSTRACT:
SUBMITTER: Schnell JR
PROVIDER: S-EPMC2253468 | biostudies-literature | 2005 Sep
REPOSITORIES: biostudies-literature
Schnell Jason R JR Zhou Guo-Ping GP Zweckstetter Markus M Rigby Alan C AC Chou James J JJ
Protein science : a publication of the Protein Society 20050901 9
Coiled-coil motifs play essential roles in protein assembly and molecular recognition, and are therefore the targets of many ongoing structural and functional studies. However, owing to the dynamic nature of many of the smaller coiled-coil domains, crystallization for X-ray studies is very challenging. Determination of elongated structures using standard NMR approaches is inefficient and usually yields low-resolution structures due to accumulation of small errors over long distances. Here we des ...[more]