Functional site prediction selects correct protein models.
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ABSTRACT:
SUBMITTER: Chelliah V
PROVIDER: S-EPMC2259414 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Publications
Functional site prediction selects correct protein models.
Chelliah Vijayalakshmi V Taylor William R WR
BMC bioinformatics 20080101
<h4>Background</h4>The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possible to predict which residues are likely to be part of a functional site and this information can be used to select model structures from a variety of alternatives that would correspond to a functional protein.<h4>Results</h4>Using a large collection of protein-like decoy models, a score was devised that selected t ...[more]
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