A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms.
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SUBMITTER: Wong GK
PROVIDER: S-EPMC2263125 | biostudies-literature | 2004 Dec
REPOSITORIES: biostudies-literature
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A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms.
Wong Gane Ka-Shu GK Liu Bin B Wang Jun J Zhang Yong Y Yang Xu X Zhang Zengjin Z Meng Qingshun Q Zhou Jun J Li Dawei D Zhang Jingjing J Ni Peixiang P Li Songgang S Ran Longhua L Li Heng H Zhang Jianguo J Li Ruiqiang R Li Shengting S Zheng Hongkun H Lin Wei W Li Guangyuan G Wang Xiaoling X Zhao Wenming W Li Jun J Ye Chen C Dai Mingtao M Ruan Jue J Zhou Yan Y Li Yuanzhe Y He Ximiao X Zhang Yunze Y Wang Jing J Huang Xiangang X Tong Wei W Chen Jie J Ye Jia J Chen Chen C Wei Ning N Li Guoqing G Dong Le L Lan Fengdi F Sun Yongqiao Y Zhang Zhenpeng Z Yang Zheng Z Yu Yingpu Y Huang Yanqing Y He Dandan D Xi Yan Y Wei Dong D Qi Qiuhui Q Li Wenjie W Shi Jianping J Wang Miaoheng M Xie Fei F Wang Jianjun J Zhang Xiaowei X Wang Pei P Zhao Yiqiang Y Li Ning N Yang Ning N Dong Wei W Hu Songnian S Zeng Changqing C Zheng Weimou W Hao Bailin B Hillier Ladeana W LW Yang Shiaw-Pyng SP Warren Wesley C WC Wilson Richard K RK Brandström Mikael M Ellegren Hans H Crooijmans Richard P M A RP van der Poel Jan J JJ Bovenhuis Henk H Groenen Martien A M MA Ovcharenko Ivan I Gordon Laurie L Stubbs Lisa L Lucas Susan S Glavina Tijana T Aerts Andrea A Kaiser Pete P Rothwell Lisa L Young John R JR Rogers Sally S Walker Brian A BA van Hateren Andy A Kaufman Jim J Bumstead Nat N Lamont Susan J SJ Zhou Huaijun H Hocking Paul M PM Morrice David D de Koning Dirk-Jan DJ Law Andy A Bartley Neil N Burt David W DW Hunt Henry H Cheng Hans H HH Gunnarsson Ulrika U Wahlberg Per P Andersson Leif L Kindlund Ellen E Tammi Martti T MT Andersson Björn B Webber Caleb C Ponting Chris P CP Overton Ian M IM Boardman Paul E PE Tang Haizhou H Hubbard Simon J SJ Wilson Stuart A SA Yu Jun J Wang Jian J Yang Huanming H
Nature 20041201 7018
We describe a genetic variation map for the chicken genome containing 2.8 million single-nucleotide polymorphisms (SNPs). This map is based on a comparison of the sequences of three domestic chicken breeds (a broiler, a layer and a Chinese silkie) with that of their wild ancestor, red jungle fowl. Subsequent experiments indicate that at least 90% of the variant sites are true SNPs, and at least 70% are common SNPs that segregate in many domestic breeds. Mean nucleotide diversity is about five SN ...[more]
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