Mucin degradation by Bifidobacterium strains isolated from the human intestinal microbiota.
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ABSTRACT:
SUBMITTER: Ruas-Madiedo P
PROVIDER: S-EPMC2268317 | biostudies-literature | 2008 Mar
REPOSITORIES: biostudies-literature
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Mucin degradation by Bifidobacterium strains isolated from the human intestinal microbiota.
Ruas-Madiedo Patricia P Gueimonde Miguel M Fernández-García María M de los Reyes-Gavilán Clara G CG Margolles Abelardo A
Applied and environmental microbiology 20080125 6
The presence of the genes engBF (endo-alpha-N-acetylgalactosaminidase) and afcA (1,2-alpha-L-fucosidase) was detected in several intestinal Bifidobacterium isolates. Two strains of Bifidobacterium bifidum contained both genes, and they were able to degrade high-molecular weight porcine mucin in vitro. The expression of both genes was highly induced in the presence of mucin. ...[more]
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