Ontology highlight
ABSTRACT:
SUBMITTER: Pande S
PROVIDER: S-EPMC2268386 | biostudies-literature | 2008 Mar
REPOSITORIES: biostudies-literature
Pande Shailja S Jain Neeraj N Prusty Bhupesh K BK Bhambhani Suresh S Gupta Sanjay S Sharma Rajyashri R Batra Swaraj S Das Bhudev C BC
Journal of clinical microbiology 20080116 3
High-risk human papillomaviruses (HPVs), particularly HPV types 16 and 18 (HPV-16 and HPV-18, respectively), play a cardinal role in the etiology of cervical cancer. The most prevalent type, HPV-16, shows intratypic sequence variants that are known to differ in oncogenic potential and geographic distribution. This study was designed to analyze sequence variations in E6, E7, and L1 genes and the LCR (for long control region) of HPV-16 in cervical cancer patients to identify the most prevalent and ...[more]