Ontology highlight
ABSTRACT:
SUBMITTER: Smith JJ
PROVIDER: S-EPMC2268513 | biostudies-literature | 2008 Mar
REPOSITORIES: biostudies-literature
Smith Joshua J JJ Torigoe Sharon E SE Maxson Julia J Fish Lisa C LC Wiley Emily A EA
Eukaryotic cell 20080104 3
Newly synthesized histones are acetylated prior to their deposition into nucleosomes. Following nucleosome formation and positioning, they are rapidly deacetylated, an event that coincides with further maturation of the chromatin fiber. The histone deacetylases (HDACs) used for histone deposition and de novo chromatin formation are poorly understood. In the ciliate Tetrahymena thermophila, transcription-related deacetylation in the macronucleus is physically separated from deposition-related dea ...[more]