Ontology highlight
ABSTRACT:
SUBMITTER: Li HX
PROVIDER: S-EPMC2271166 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Li Hai-Xin HX Hwang Bum-Yeol BY Laxmikanthan Gurunathan G Blaber Sachiko I SI Blaber Michael M Golubkov Pavel A PA Ren Pengyu P Iverson Brent L BL Georgiou George G
Protein science : a publication of the Protein Society 20080401 4
The human tissue kallikrein (KLK) family contains 15 secreted serine proteases that are expressed in a wide range of tissues and have been implicated in different physiological functions and disease states. Of these, KLK1 has been shown to be involved in the regulation of multiple physiological processes such as blood pressure, smooth muscle contraction, and vascular cell growth. KLK6 is overexpressed in breast and ovarian cancer tissues and has been shown to cleave peptide derived from human my ...[more]