Ontology highlight
ABSTRACT:
SUBMITTER: Schuppan D
PROVIDER: S-EPMC2271178 | biostudies-literature | 2008 Mar
REPOSITORIES: biostudies-literature
Lancet (London, England) 20080301 9615
Cirrhosis is defined as the histological development of regenerative nodules surrounded by fibrous bands in response to chronic liver injury, which leads to portal hypertension and end-stage liver disease. Recent advances in the understanding of the natural history and pathophysiology of cirrhosis, and in treatment of its complications, have resulted in improved management, quality of life, and life expectancy of patients. Liver transplantation remains the only curative option for a selected gro ...[more]