Ontology highlight
ABSTRACT:
SUBMITTER: Kumaran D
PROVIDER: S-EPMC2279289 | biostudies-literature | 2005 Mar
REPOSITORIES: biostudies-literature
Kumaran Desigan D Eswaramoorthy Subramaniam S Studier F William FW Swaminathan Subramanyam S
Protein science : a publication of the Protein Society 20050301 3
Appr-1''-pase, an important and ubiquitous cellular processing enzyme involved in the tRNA splicing pathway, catalyzes the conversion of ADP-ribose-1''monophosphate (Appr-1''-p) to ADP-ribose. The structures of the native enzyme from the yeast and its complex with ADP-ribose were determined to 1.9 A and 2.05 A, respectively. Analysis of the three-dimensional structure of this protein, selected as a target in a structural genomics project, reveals its putative function and provides clues to the c ...[more]