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ABSTRACT:
SUBMITTER: Ponnuvel KM
PROVIDER: S-EPMC228431 | biostudies-literature | 2003 Oct
REPOSITORIES: biostudies-literature
Ponnuvel Kangayam M KM Nakazawa Hiroshi H Furukawa Seiichi S Asaoka Ai A Ishibashi Jun J Tanaka Hiromitsu H Yamakawa Minoru M
Journal of virology 20031001 19
A protein showing strong antiviral activity against Bombyx mori nucleopolyhedrovirus (BmNPV) was purified from the digestive juice of B. mori larvae. A homology search of the deduced amino acid sequence of the protein cDNA revealed 56% homology with Drosophila melanogaster lipase and 21% homology with human lipase. As lipase activity of the protein was confirmed in vitro, this protein was designated Bmlipase-1. Northern blot analysis showed that the Bmlipase-1 gene is expressed in the midgut but ...[more]