Free recombination within Helicobacter pylori.
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ABSTRACT:
SUBMITTER: Suerbaum S
PROVIDER: S-EPMC22880 | biostudies-literature | 1998 Oct
REPOSITORIES: biostudies-literature
Publications
Free recombination within Helicobacter pylori.
Suerbaum S S Smith J M JM Bapumia K K Morelli G G Smith N H NH Kunstmann E E Dyrek I I Achtman M M
Proceedings of the National Academy of Sciences of the United States of America 19981001 21
Sequences of three gene fragments (flaA, flaB, and vacA) from Helicobacter pylori strains isolated from patients in Germany, Canada, and South Africa were analyzed for diversity and for linkage equilibrium by using the Homoplasy Test and compatibility matrices. Horizontal genetic exchange in H. pylori is so frequent that different loci and polymorphisms within each locus are all at linkage equilibrium. These results indicate that H. pylori is panmictic. Comparisons with sequences from Escherichi ...[more]
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