Ontology highlight
ABSTRACT:
SUBMITTER: Parmakelis A
PROVIDER: S-EPMC2288592 | biostudies-literature | 2008 Mar
REPOSITORIES: biostudies-literature
Parmakelis Aristeidis A Slotman Michel A MA Marshall Jonathon C JC Awono-Ambene Parfait H PH Antonio-Nkondjio Christophe C Simard Frederic F Caccone Adalgisa A Powell Jeffrey R JR
BMC evolutionary biology 20080306
<h4>Background</h4>If the insect innate immune system is to be used as a potential blocking step in transmission of malaria, then it will require targeting one or a few genes with highest relevance and ease of manipulation. The problem is to identify and manipulate those of most importance to malaria infection without the risk of decreasing the mosquito's ability to stave off infections by microbes in general. Molecular evolution methodologies and concepts can help identify such genes. Within th ...[more]