PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease.
Ontology highlight
ABSTRACT:
SUBMITTER: Cresci S
PROVIDER: S-EPMC2288645 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Publications
PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease.
PPAR research 20080101
The peroxisome proliferator-activated receptors (PPARs) consist of three related transcription factors that serve to regulate a number of cellular processes that are central to cardiovascular health and disease. Numerous pharmacologic studies have assessed the effects of specific PPAR agonists in clinical trials and have provided insight into the clinical effects of these genes while genetic studies have demonstrated clinical associations between PPAR polymorphisms and abnormal cardiovascular ph ...[more]
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