Role of the AheABC efflux pump in Aeromonas hydrophila intrinsic multidrug resistance.
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SUBMITTER: Hernould M
PROVIDER: S-EPMC2292534 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
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Role of the AheABC efflux pump in Aeromonas hydrophila intrinsic multidrug resistance.
Hernould Mathieu M Gagné Séverine S Fournier Michel M Quentin Claudine C Arpin Corinne C
Antimicrobial agents and chemotherapy 20080211 4
Gene inactivation and complementation experiments showed that the tripartite AheABC efflux pump of Aeromonas hydrophila extruded at least 13 substrates, including nine antibiotics. The use of phenylalanine-arginine-beta-naphthylamide (PAbetaN) revealed an additional system(s) contributing to intrinsic resistance. This is the first analysis of the role of multidrug efflux systems in Aeromonas spp. ...[more]
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