Peropsin, a novel visual pigment-like protein located in the apical microvilli of the retinal pigment epithelium.
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ABSTRACT:
SUBMITTER: Sun H
PROVIDER: S-EPMC23288 | biostudies-literature | 1997 Sep
REPOSITORIES: biostudies-literature
Publications
Peropsin, a novel visual pigment-like protein located in the apical microvilli of the retinal pigment epithelium.
Sun H H Gilbert D J DJ Copeland N G NG Jenkins N A NA Nathans J J
Proceedings of the National Academy of Sciences of the United States of America 19970901 18
A visual pigment-like protein, referred to as peropsin, has been identified by large-scale sequencing of cDNAs derived from human ocular tissues. The corresponding mRNA was found only in the eye, where it is localized to the retinal pigment epithelium (RPE). Peropsin immunoreactivity, visualized by light and electron microscopy, localizes the protein to the apical face of the RPE, and most prominently to the microvilli that surround the photoreceptor outer segments. These observations suggest th ...[more]
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