Ontology highlight
ABSTRACT:
SUBMITTER: Lombaert IM
PROVIDER: S-EPMC2329592 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Lombaert Isabelle M A IM Brunsting Jeanette F JF Wierenga Pieter K PK Faber Hette H Stokman Monique A MA Kok Tineke T Visser Willy H WH Kampinga Harm H HH de Haan Gerald G Coppes Robert P RP
PloS one 20080430 4
Head and neck cancer is the fifth most common malignancy and accounts for 3% of all new cancer cases each year. Despite relatively high survival rates, the quality of life of these patients is severely compromised because of radiation-induced impairment of salivary gland function and consequential xerostomia (dry mouth syndrome). In this study, a clinically applicable method for the restoration of radiation-impaired salivary gland function using salivary gland stem cell transplantation was devel ...[more]