Ontology highlight
ABSTRACT:
SUBMITTER: Singh RK
PROVIDER: S-EPMC2330204 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Singh Rajesh Kumar RK Palm Gottfried J GJ Panjikar Santosh S Hinrichs Winfried W
Acta crystallographica. Section F, Structural biology and crystallization communications 20070312 Pt 4
Crystal structure determination of catabolite control protein A (CcpA) at 2.6 A resolution reveals for the first time the structure of a full-length apo-form LacI-GalR family repressor protein. In the crystal structures of these transcription regulators, the three-helix bundle of the DNA-binding domain has only been observed in cognate DNA complexes; it has not been observed in other crystal structures owing to its mobility. In the crystal packing of apo-CcpA, the protein-protein contacts betwee ...[more]