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Coupling of activated esters to gramines in the presence of ethyl propiolate under mild conditions.


ABSTRACT: The coupling of activated esters to gramine derivatives is described using ethyl propiolate. A series of substrates have been prepared using these mild conditions to provide a scope and limitations for this methodology.

SUBMITTER: Jones DT 

PROVIDER: S-EPMC2346430 | biostudies-literature | 2007 Feb

REPOSITORIES: biostudies-literature

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Coupling of activated esters to gramines in the presence of ethyl propiolate under mild conditions.

Jones David T DT   Artman Gerald D GD   Williams Robert M RM  

Tetrahedron letters 20070201 7


The coupling of activated esters to gramine derivatives is described using ethyl propiolate. A series of substrates have been prepared using these mild conditions to provide a scope and limitations for this methodology. ...[more]

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