Ontology highlight
ABSTRACT:
SUBMITTER: Rantanen MK
PROVIDER: S-EPMC2361094 | biostudies-literature | 2007 Jun
REPOSITORIES: biostudies-literature
Rantanen Mika K MK Lehtiö Lari L Rajagopal Lakshmi L Rubens Craig E CE Goldman Adrian A
The FEBS journal 20070522 12
We solved the crystal structure of Streptococcus agalactiae serine/threonine phosphatase (SaSTP) using a combination of single-wavelength anomalous dispersion phasing and molecular replacement. The overall structure resembles that of previously characterized members of the PPM/PP2C STP family. The asymmetric unit contains four monomers and we observed two novel conformations for the flap domain among them. In one of these conformations, the enzyme binds three metal ions, whereas in the other it ...[more]