Ontology highlight
ABSTRACT:
SUBMITTER: Parks BA
PROVIDER: S-EPMC2361135 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
Parks Bryan A BA Jiang Lihua L Thomas Paul M PM Wenger Craig D CD Roth Michael J MJ Boyne Michael T MT Burke Patricia V PV Kwast Kurt E KE Kelleher Neil L NL
Analytical chemistry 20071005 21
Proteomics has grown significantly with the aid of new technologies that consistently are becoming more streamlined. While processing of proteins from a whole cell lysate is typically done in a bottom-up fashion utilizing MS/MS of peptides from enzymatically digested proteins, top-down proteomics is becoming a viable alternative that until recently has been limited largely to offline analysis by tandem mass spectrometry. Here we describe a method for high-resolution tandem mass spectrometery of ...[more]