Ontology highlight
ABSTRACT:
SUBMITTER: Zhu H
PROVIDER: S-EPMC2362140 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Zhu Haiyan H Taylor Jennie W JW Bennett David A DA Younkin Steven G SG Estus Steven S
Neurobiology of aging 20061218 5
Several polymorphisms in hepatic lipase (LIPC) are similar to apoE4 because they associate with cholesterol concentrations and, for rs6084, coronary artery disease (CAD). Since apoE4 is also a primary genetic risk factor for late-onset Alzheimer's disease (LOAD), LIPC single nucleotide polymorphisms (SNP)s represent excellent candidates for LOAD association studies. Because this issue has not been addressed previously, we evaluated LIPC SNP association with LOAD. In a population from the Religio ...[more]