Ontology highlight
ABSTRACT:
SUBMITTER: Gomes CM
PROVIDER: S-EPMC2373467 | biostudies-literature | 2002 Mar
REPOSITORIES: biostudies-literature
Gomes Cláudio M CM Frazão Carlos C Xavier António V AV Legall Jean J Teixeira Miguel M
Protein science : a publication of the Protein Society 20020301 3
At present there are three protein families that share a common structural domain, the alphabeta/betaalpha fold of class B beta-lactamases: zinc beta-lactamases, glyoxalases II, and A-type flavoproteins. A detailed inspection of their superimposed structures was undertaken and showed that although these proteins contain binuclear metal sites in spatially equivalent positions, there are some subtle differences within the first ligand sphere that determine a distinct composition of metals. Althoug ...[more]