Ontology highlight
ABSTRACT:
SUBMITTER: Matynia A
PROVIDER: S-EPMC2373872 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Matynia Anna A Anagnostaras Stephan G SG Wiltgen Brian J BJ Lacuesta Maress M Fanselow Michael S MS Silva Alcino J AJ
PloS one 20080507 5
Previous studies have revealed that the initial stages of memory formation require several genes involved in synaptic, transcriptional and translational mechanisms. In contrast, very little is known about the molecular and cellular mechanisms underlying later stages of memory, including remote memory (i.e. 7-day memory). To identify genes required for remote memory, we screened randomly selected mouse strains harboring known mutations. In our primary reverse genetic screen, we identified 4 putat ...[more]