Ontology highlight
ABSTRACT:
SUBMITTER: Lu J
PROVIDER: S-EPMC2374378 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Bioinformation 20080428 7
The accurate identification of promoter regions and transcription start sites is a challenge to the construction of human transcription regulation networks. Thus, an efficient prediction method based on theoretical formulation is necessary for this purpose. We used the method of increment diversity with quadratic discriminant analysis (IDQD) to predict transcription start sites (TSS). The method produced sensitivity and positive predictive value of more than 65% with positives to negatives ratio ...[more]