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Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes.

ABSTRACT: Metazoan genomes contain arrays of highly conserved noncoding elements (HCNEs) that span developmental regulatory genes and define regulatory domains. We describe Ancora http://ancora.genereg.net, a web resource that provides data and tools for exploring genomic organization of HCNEs for multiple genomes. Ancora includes a genome browser that shows HCNE locations and features novel HCNE density plots as a powerful tool to discover developmental regulatory genes and distinguish their regulatory elements and domains.

SUBMITTER: Engstrom PG

PROVIDER: S-EPMC2374709 | biostudies-literature | 2008

REPOSITORIES: biostudies-literature

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Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes.

Engström Pär G PG Fredman David D Lenhard Boris B

Genome biology 20080215 2

Metazoan genomes contain arrays of highly conserved noncoding elements (HCNEs) that span developmental regulatory genes and define regulatory domains. We describe Ancora http://ancora.genereg.net, a web resource that provides data and tools for exploring genomic organization of HCNEs for multiple genomes. Ancora includes a genome browser that shows HCNE locations and features novel HCNE density plots as a powerful tool to discover developmental regulatory genes and distinguish their regulatory e ...[more]

PMID: 18279518

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