Ontology highlight
ABSTRACT:
SUBMITTER: Carneiro A
PROVIDER: S-EPMC2374796 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Carneiro Ana A Isinger Anna A Karlsson Anna A Johansson Jan J Jönsson Göran G Bendahl Pär-Ola PO Falkenback Dan D Halvarsson Britta B Nilbert Mef M
BMC cancer 20080411
<h4>Background</h4>Esophageal squamous cell carcinoma (ESCC) is a genetically complex tumor type and a major cause of cancer related mortality. Although distinct genetic alterations have been linked to ESCC development and prognosis, the genetic alterations have not gained clinical applicability. We applied array-based comparative genomic hybridization (aCGH) to obtain a whole genome copy number profile relevant for identifying deranged pathways and clinically applicable markers.<h4>Methods</h4> ...[more]