Ontology highlight
ABSTRACT:
SUBMITTER: Rubins KH
PROVIDER: S-EPMC2375004 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
Rubins Kathleen H KH Hensley Lisa E LE Wahl-Jensen Victoria V Daddario DiCaprio Kathleen M KM Young Howard A HA Reed Douglas S DS Jahrling Peter B PB Brown Patrick O PO Relman David A DA Geisbert Thomas W TW
Genome biology 20070101 8
<h4>Background</h4>Infection with Ebola virus (EBOV) causes a fulminant and often fatal hemorrhagic fever. In order to improve our understanding of EBOV pathogenesis and EBOV-host interactions, we examined the molecular features of EBOV infection in vivo.<h4>Results</h4>Using high-density cDNA microarrays, we analyzed genome-wide host expression patterns in sequential blood samples from nonhuman primates infected with EBOV. The temporal program of gene expression was strikingly similar between a ...[more]