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The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists.

ABSTRACT: The DAVID Gene Functional Classification Tool http://david.abcc.ncifcrf.gov uses a novel agglomeration algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. This organization is accomplished by mining the complex biological co-occurrences found in multiple sources of functional annotation. It is a powerful method to group functionally related genes and terms into a manageable number of biological modules for efficient interpretation of gene lists in a network context.

SUBMITTER: Huang DW

PROVIDER: S-EPMC2375021 | biostudies-literature | 2007

REPOSITORIES: biostudies-literature

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The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists.

Huang Da Wei DW Sherman Brad T BT Tan Qina Q Collins Jack R JR Alvord W Gregory WG Roayaei Jean J Stephens Robert R Baseler Michael W MW Lane H Clifford HC Lempicki Richard A RA

Genome biology 20070101 9

The DAVID Gene Functional Classification Tool http://david.abcc.ncifcrf.gov uses a novel agglomeration algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. This organization is accomplished by mining the complex biological co-occurrences found in multiple sources of functional annotation. It is a powerful method to group functionally related genes and terms into a manageable number of biological module ...[more]

PMID: 17784955

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