Ontology highlight
ABSTRACT:
SUBMITTER: Jung J
PROVIDER: S-EPMC2376330 | biostudies-literature | 2007 Sep
REPOSITORIES: biostudies-literature
Acta crystallographica. Section F, Structural biology and crystallization communications 20070831 Pt 9
Nudix hydrolases are a family of proteins that contain the characteristic amino-acid sequence GX(5)EX(7)REUXEEXGU (where U is usually I, L or V), the Nudix signature sequence. They catalyze the hydrolysis of a variety of nucleoside diphosphate derivatives such as nucleoside triphosphates, nucleotide sugars, ADP-ribose, dinucleotide coenzymes, diadenosine oligophosphates and capped RNAs. Recently, three new Nudix hydrolases have been found from Escherichia coli; one of them is Orf141, which cleav ...[more]