Ontology highlight
ABSTRACT:
SUBMITTER: Zhang L
PROVIDER: S-EPMC2383982 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Zhang Lin L Volinia Stefano S Bonome Tomas T Calin George Adrian GA Greshock Joel J Yang Nuo N Liu Chang-Gong CG Giannakakis Antonis A Alexiou Pangiotis P Hasegawa Kosei K Johnstone Cameron N CN Megraw Molly S MS Adams Sarah S Lassus Heini H Huang Jia J Kaur Sippy S Liang Shun S Sethupathy Praveen P Leminen Arto A Simossis Victor A VA Sandaltzopoulos Raphael R Naomoto Yoshio Y Katsaros Dionyssios D Gimotty Phyllis A PA DeMichele Angela A Huang Qihong Q Bützow Ralf R Rustgi Anil K AK Weber Barbara L BL Birrer Michael J MJ Hatzigeorgiou Artemis G AG Croce Carlo M CM Coukos George G
Proceedings of the National Academy of Sciences of the United States of America 20080505 19
MicroRNAs (miRNAs) are an abundant class of small noncoding RNAs that function as negative gene regulators. miRNA deregulation is involved in the initiation and progression of human cancer; however, the underlying mechanism and its contributions to genome-wide transcriptional changes in cancer are still largely unknown. We studied miRNA deregulation in human epithelial ovarian cancer by integrative genomic approach, including miRNA microarray (n = 106), array-based comparative genomic hybridizat ...[more]