Ontology highlight
ABSTRACT:
SUBMITTER: Kamotani Y
PROVIDER: S-EPMC2386516 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Kamotani Yoko Y Bersano-Begey Tommaso T Kato Nobuhiro N Tung Yi-Chung YC Huh Dongeun D Song Jonathan W JW Takayama Shuichi S
Biomaterials 20080314 17
Cell culture systems are often static and are therefore nonphysiological. In vivo, many cells are exposed to dynamic surroundings that stimulate cellular responses in a process known as mechanotransduction. To recreate this environment, stretchable cell culture substrate systems have been developed, however, these systems are limited by being macroscopic and low throughput. We have developed a device consisting of 24 miniature cell stretching chambers with flexible bottom membranes that are defo ...[more]