Ontology highlight
ABSTRACT:
SUBMITTER: Oneda B
PROVIDER: S-EPMC2386549 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Oneda Beatrice B Lods Nadège N Lottaz Daniel D Becker-Pauly Christoph C Stöcker Walter W Pippin Jeffrey J Huguenin Maya M Ambort Daniel D Marti Hans-Peter HP Sterchi Erwin E EE
PloS one 20080528 5
Meprin (EC 3.4.24.18) is an oligomeric metalloendopeptidase found in microvillar membranes of kidney proximal tubular epithelial cells. Here, we present the first report on the expression of meprin beta in rat glomerular epithelial cells and suggest a potential involvement in experimental glomerular disease. We detected meprin beta in glomeruli of immunostained rat kidney sections on the protein level and by quantitative RT-PCR of laser-capture microdissected glomeruli on the mRNA level. Using i ...[more]