Ontology highlight
ABSTRACT:
SUBMITTER: Liu XQ
PROVIDER: S-EPMC2386732 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Liu Xiao-Qing XQ Paterson Andrew D AD He Ning N St George-Hyslop Peter P Rauta Virpi V Gronhagen-Riska Carola C Laakso Markku M Thibaudin Lise L Berthoux Francois F Cattran Daniel D Pei York Y
Journal of the American Society of Nephrology : JASN 20080206 5
Familial clustering and genome-wide linkage scans strongly support a genetic susceptibility to familial IgA nephropathy (IgAN), but genetic factors that predispose to sporadic IgAN are unknown. A high-throughput single nucleotide polymorphism (SNP) association study was conducted using a customized Illumina BeadChip in 732 white patients with biopsy-proven IgAN and 503 control subjects from Canada, France, and Finland. Approximately 93% of 1536 SNPs on the array were tag SNPs from Phase I+II of ...[more]